How Antibiotics For Chlamydia Work
Chlamydia is caused by a bacteria called Chlamydia trachomatis.
In the body, an infection spreads when the bacterial cells causing it multiply. The way antibiotics work in stopping the spread, is to prevent the bacteria from producing certain proteins. The bacterial cells need these proteins to sustain themselves and grow but by stopping the bacteria from generating them, the antibiotic agent helps to stop the bacteria from growing, and spreading the infection. The immune system is then able to fight off the infection and symptoms start to clear up.
What Dosage Treats Chlamydia
For people with uncomplicated genital chlamydia, the Centers for Disease Control and Prevention recommends a single dose of azithromycin taken orally to cure the infection.
Azithromycin comes in three forms:
- Regular-release powder
For both powder formulas, either you or a pharmacist mix it with liquid to take.
Always follow the directions from your doctor or pharmacist for taking azithromycin.
Azithromycin is taken as a single dose, one time.
It should be taken as soon as you receive the prescription. Azithromycin can be taken with or without food, however, the extended-release form is typically taken on an empty stomach.
If you take the liquid form, shake it well before using and use a dosing spoon to measure an accurate dose. If you are prescribed the powder, mix it with water according to directions.
When Can I Have Sex Again
If you had doxycycline, you shouldn’t have sex including vaginal, oral or anal sex, even with a condom until both you and your partner have completed treatment.
If you had azithromycin, you should wait 7 days after treatment before having sex .
This will help ensure you don’t pass on the infection or catch it again straight away.
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How Is Chlamydia Diagnosed
Chlamydia can be diagnosed with either a first-catch urine test or a swab collected from the endocervix or vagina in women, or a first-catch urine test or a swab collected from the urethra in men.
Self-collected vaginal swab testing is available and many women find this screening strategy highly acceptable.
- Geisler WM, Uniyal A, Lee JY, et al. Azithromycin versus Doxycycline for Urogenital Chlamydia trachomatis Infection. N Engl J Med. 2015 373:2512-2521. doi:10.1056/NEJMoa1502599
- Workowski, K, Bolan G. U.S. Department of Health and Human Services. Sexually Transmitted Diseases Treatment Guidelines, 2015. Morbidity and Mortality Weekly Report.
- WHO Guidelines for the Treatment of Chlamydia trachomatis. Geneva: World Health Organization 2016. 4, RECOMMENDATIONS FOR TREATMENT OF CHLAMYDIAL INFECTIONS. Available from:
- Chlamydia Treatment and Care. Centers for Disease Control and Prevention https://www.cdc.gov/std/chlamydia/treatment.htm
- Chlamydia Treatment Information Sheet. Wisconsin Department of Health Services.
Management Of Sex Partners
Sex partners should be referred for evaluation, testing, and presumptive treatment if they had sexual contact with the partner during the 60 days preceding the patients onset of symptoms or chlamydia diagnosis. Although the exposure intervals defining identification of sex partners at risk are based on limited data, the most recent sex partner should be evaluated and treated, even if the time of the last sexual contact was > 60 days before symptom onset or diagnosis.
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Male Issues Of Untreated Chlamydia
Male can additionally experience issues when chlamydia is left neglected. The epididymis the tube that holds the testicles in position may end up being inflamed, triggering pain. This is referred to as epididymitis.
The infection can additionally spread to the prostate gland, creating a fever, unpleasant intercourse, and discomfort in the lower back. Another possible problem is male chlamydial urethritis.
These are just some of one of the most typical issues of unattended chlamydia, which is why it is necessary to get medical attention right away. Lots of people who get therapy quickly have no long-lasting clinical troubles. What Is The Best Antibiotic For Chlamydia
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Hi there, Im Melissa and welcome to Genier. Im not ashamed to admit that Ive dealt with an STD before and recovered. It was not a pleasant experience but Im glad I got myself tested. If theres one message that you can take away from my site is get tested today! Stay safe.
Long Term Complications Of Chlamydia In Males
In men, chlamydia can be diagnosed from a urine test / swab, even if you have no symptoms. In 50% of men who test positive, chlamydia symptoms are absent. However if untreated, because chlamydia also causes inflammation in the male genital tract, this may result in the following.
- Urethritis pain within the penis and on passing urine, often with discharge
- Epididymo-orchitis painful, swollen testicles
- Prostatitis a painful, swollen, prostate gland
- Chlamydial infection also affects male fertility. Semen is poorer quality, and as it is packed full of inflammatory cells, sperm are less ability to swim freely.
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The Costs Of Infertility
Treating chlamydia is easy, but for those who do not get treated or get treated too late, living with the damage caused by the infection can be hard.
Rabin has treated many women who never knew they had had chlamydia until they couldnt get pregnant due to blocked fallopian tubes. These women often wind up trying in vitro fertilization , which does not always succeed.
There are all kinds of costs involved for these women, say Rabin. There are emotional costs and physical costs. There are also financial costs with IVF. Its much better to not let the tubes get damaged, she says, and get pregnant the old-fashioned way.
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How Does Chlamydia Impact Pregnancy
Pregnant women who have been treated for chlamydia should return after three weeks to be retested to establish that they have been cured. They should return again after three months to evaluate for reinfection. Untreated chlamydia in pregnant women can lead to early rupture of the fluid sac containing the fetus and premature delivery. It can also lead to pneumonia or conjunctivitis in the newborn .
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How To Take It
Azithromycin is taken one time orally and can be taken with or without food. Its important to take it as directed by your doctor.
It takes approximately 1 week for azithromycin to cure chlamydia. Avoid having sex while under treatment, as its still possible to pass or worsen the infection during treatment.
Sex Partners Need Treatment Too
If you are diagnosed with chlamydia, you will need to tell all of your sexual partners, because they will need the same treatment you are receiving.
In most states, a doctor or other healthcare provider can give you the medicine that your partner or partners will need to take. Then you can deliver it to those partners. This practice is called expedited partner therapy or patient delivered partner therapy.
These options can help a lot if your partner doesnt have a healthcare provider or feels embarrassed about seeking care, says Dr. Dombrowski.
Its natural to feel nervous or upset about having to tell your partner or partners about having an STD. Your healthcare provider can help with this problem. They may even rehearse the conversation with you, says Dombrowksi.
Learning about chlamydia and seeking advice from a healthcare provider about how to discuss it with your partner can help you handle the conversation with less anxiety and more confidence.
Remember, chlamydia is not just common: It is the most common infection reported to the Centers for Disease Control and Prevention . You are being helpful, mature, and responsible by telling your partners.
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The Best Antibiotics For Chlamydia: First
Chlamydia can be easily treated and cured with antibiotics. However, not all antibiotics are effective.
The Centers for Disease Control and Prevention recommends doxycycline or azithromycin as first-choice antibiotic for the treatment of genital chlamydia. These medications are very effective for both acute and persistent infections.
Important note: To avoid reinfection, persons with chlamydia should abstain from sexual activity until they and their sex partners have completed the treatment.
Get Chlamydia Treatment Online
Get chlamydia treatment online by speaking to a board-certified doctor, securely from your phone or computer. Our licensed doctors can provide you with a lab order for testing and once diagnosed, treat chlamydia, including writing prescriptions for any necessary medication.
We accept these insurance plans and many more. Without insurance, appointments are $119.
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Can You Drink Alcohol While Taking Azithromycin For Chlamydia
Yes, you may drink a small amount of alcohol while you are taking azithromycin but there is a chance large amounts of alcohol may increase the gastrointestinal side effects of azithromycin, such as nausea, diarrhea, vomiting, abdominal pain, dyspepsia, or flatulence. Too much alcohol with azithromycin may also give you a headache.
Because azithromycin is usually taken as a one-off dose, drinking alcohol is unlikely to stop azithromycin from curing chlamydia.
Study Design And Setting
This is a double-blind RCT. Given our primary outcome is treatment efficacy, our trial is double blind to minimize bias that could arise as a result of the different dosing regimens of the two drugs . For example: i) it is possible that taking a 7-day course of daily doxycycline rather than a single dose of azithromycin may deter people from resuming sexual activity while taking treatment, thereby reducing their risk of a new infection, and ii) participants could be less adherent to a 7-day regimen which could impact efficacy . The trial will be conducted within sexual health clinics in Victoria and New South Wales in Australia and in accordance with the Declaration of Helsinki. The trial was approved by the Alfred Hospital Ethics Committee .
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What Is The Dosage Of Azithromycin For Chlamydia
The recommended dosage of azithromycin for chlamydia is 1 gram as a single dose. This dose may be taken morning or night and can be taken with or without food. Another name for azithromycin is Zithromax.
If you have taken your dose of azithromycin on an empty stomach and your stomach has become a bit upset or you feel sick, it is Ok to eat some food, which may help to settle it.
A 500mg dose of azithromycin is not recommended by guidelines to cure chlamydia. There is also a chance it may increase the risk of C. trachomatis bacteria becoming resistant to it. If you have only taken or only been prescribed a 500mg dose of azithromycin, you need to return to your doctor to get a 1 gram dose prescribed. You should never share your dose of azithromycin with another person.
How Does Chlamydia Treatment Work
Chlamydia treatment works by stopping the bacteria that causes chlamydia from producing an important protein which it needs to multiply. This stops the bacteria from growing and replicating, so your symptoms should improve as your body is cleared of chlamydia.
The first line treatment for chlamydia in the UK is doxycycline. The usual dose is one tablet to be taken twice daily for 7 days. You can swallow doxycycline tablets whole with water and take them with or without food. You should sit up for about 30 minutes after each dose to prevent symptoms of throat irritation or stomach upset.
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What Are The Best Antibiotics For Chlamydia
While there are numerous antibiotics available to treat bacterial infections, certain types are considered to be the best for treatment of chlamydia. The two first-choice antibiotics for chlamydia prescribed by most doctors are azithromycin and doxycycline. Erythromycin, ofloxacin and levofloxacin are all drugs that may also be prescribed, and amoxicillin is sometimes used to treat women who are pregnant. Each medication has pros and cons in regards to dosing regimen, price, and side effects.
Azithromycin is considered one of the two best antibiotics for chlamydia treatment. It is very easy to take, only requiring a single dose, and cures the disease in 95% of cases. People with chronic, recurring cases of chlamydia do particularly well when treated with this drug, and it is considered safe to be used during pregnancy. The disadvantages of the drug are that it tends to be more expensive than other treatments, and may cause nausea or vomiting.
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Doxycycline Resistance And T Pallidum
Although serological failure, defined as a lack of 4-fold decline in rapid plasma reagin titres following therapy, was observed in patients treated with doxycycline , no resistance study that could explain treatment failure was conducted and currently a unique study concerns doxycycline resistance of T. pallidum. In this study, Xiao et al. investigated the presence of the G1058C point mutation in the 16S rRNA gene associated with decreased susceptibility to doxycycline and found no mutation among 2253 whole blood specimens sampled from Chinese patients with secondary or latent syphilis between 2013 and 2015.
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Treating Other Types Of Chlamydial Infections
Two other conditions caused by Chlamydia trachomatis are uncommon in the United States, but very common worldwide:
- Lymphogranuloma venereum : Lymphogranuloma venereum is treated in the same way as standard genital chlamydia infections, but a longer course of therapy is used . Other care may also be required to treat genital ulcers or abscessed inguinal nodes if they occur.
- Trachoma: Trachoma is the leading preventable cause of blindness worldwide and often requires aggressive treatment with antibiotics and surgery addressing unsanitary living conditions is also necessary.
Use In Pregnancy And Breastfeeding
Doxycycline is labelled as Pregnancy Category D in the FDA classification. So, doxycycline should be avoided during pregnancy because of severe adverse effects including teratogenicity, permanent yellowish-brown teeth discoloration after in utero exposure and rare fatal hepatotoxicity, and is therefore contraindicated past the fifth week of pregnancy. However, despite this categorization as a class D agent, doxycycline was FDA approved for use in pregnant women following exposure to biothreat agents, including Bacillus anthracis, Yersinia pestis and Francisella tularensis.
Recently, a systematic review of doxycycline in pregnant women revealed a safety profile significantly different from that of tetracycline with no correlation between the use of doxycycline and teratogenic effects during pregnancy or dental staining in children.
Although doxycycline produces measurable milk levels, it is not contraindicated during the nursing period.
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So What Is The Best Treatment For Chlamydia
Current guidance from both the National Institute of Clinical Excellence and the British Association for Sexual Health and HIV, state that doxycycline is the preferred and first-line treatment for chlamydia. This is due to antibiotic resistance, as research has shown that chlamydia responds better to doxycycline. Azithromycin should be used where doxycycline is not safe to be prescribed, and for patients who may experience difficulty in sticking to a one-week regime. To find out more information, you can visit our chlamydia FAQâs.
Whilst all of our content is written and reviewed by healthcare professionals, it is not intended to be substituted for or used as medical advice. If you have any questions or concerns about your health, please speak to your doctor.
How Do I Know If I Have Chlamydia
If you suspect you have chlamydia, your doctor may want to test cervical or penile discharge or urine using one of several available methods.
In most cases of chlamydia, the cure rate is 95%. However, because many women don’t know they have the disease until it has caused serious complications such as pelvic inflammatory disease, sexually active women under age 25 and others at higher risk should be tested for chlamydia once a year during their annual pelvic exam even if they dont have symptoms.
Pregnant women should also be tested as part of their routine lab work.
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Chlamydia Treatment And Prevention
Milly DawsonSanjai Sinha, MDShutterstock
Chlamydia is easy to cure. If you test positive for chlamydia, basically you take an antibiotic, says Jill Rabin, MD, cochief in the division of ambulatory care for women’s health programs and prenatal care assistance program services for Northwell Health in New Hyde Park, New York.
Your partner must take an antibiotic, too, to keep them from reinfecting you, she says.
You have to have your partner treated, and if you have more than one partner, they should all be treated, says Dr. Rabin, regardless of your partners genders.
Even if you dont have chlamydia now, its wise to learn how to protect yourself so you wont develop this common infection in the first place. In women, chlamydia can create serious health problems, including infertility. Besides, no one ever wants to have a sexually transmitted disease and then have to tell other people about it.
How To Cope With Side Effects
What to do about:
- feeling sick stick to simple meals and do not eat rich or spicy food while youre taking this medicine.
- diarrhoea or being sick drink lots of fluids such as water or squash to avoid dehydration. Take small, frquent sips if youre being sick. Signs of dehydration include peeing less than usual or having strong-smelling pee. Do not take any other medicines to treat diarrhoea or vomiting without speaking to a pharmacist or doctor.
- losing your appetite eat when you would usually expect to be hungry. If it helps, eat smaller meals more often than usual. Snack when youre hungry. Have nutritious snacks that are high in calories and protein, such as dried fruit and nuts.
- headaches rest and drink plenty of water. Ask your pharmacist to recommend a painkiller if you need one. Talk to your doctor if the headaches last longer than a week or are severe.
- feeling dizzy or tired if you feel dizzy when you stand up, try getting up very slowly or stay sitting down until you feel better. If you begin to feel dizzy, lie down so you dont faint, then sit until you feel better. Do not drive or use tools or machines if you feel dizzy or tired. Do not drink alcohol as it may make you feel worse.
- changes to your sense of taste talk with your doctor if this is bothering you.
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